Brendon also continued acting beyond *Buffy the Vampire Slayer*, appearing in projects such as *Kitchen Confidential* and *Criminal Minds*, where he portrayed technical analyst Kevin Lynch. In the years before his death, he faced several personal and health challenges while continuing to pursue creative interests, including painting and art. According to later reports, the coroner determined that cardiovascular disease was the primary cause of death, with acute pneumonia and a previous heart attack listed as contributing factors.
His performances remain part of a television era that continues to attract both longtime fans and new audiences. Through Xander Harris, Brendon portrayed a character who was imperfect, humorous, vulnerable, and often courageous when it mattered most. His family has asked for privacy as they remember him, while viewers around the world continue to revisit his work and the characters he brought to life, ensuring that his contribution to television will remain remembered for years to come.