Eric Dane died on February 19, 2026, following a battle with amyotrophic lateral sclerosis, according to his family’s confirmation. He was 53. For many viewers, he will remain inseparable from Dr. Mark Sloan, the charismatic Grey’s Anatomy surgeon whose “McSteamy” nickname became part of the show’s identity. His later portrayal of Cal Jacobs on Euphoria brought him to audiences in a markedly different role, revealing another side of the actor they thought they knew.